Deregulation of Interferon Signaling in Malignant Cells

Interferons (IFNs) are a family of cytokines with potent antiproliferative, antiviral, and immunomodulatory properties.Much has been learned about IFNs and IFN-activated Straws signaling cascades over the last 50 years.Due to their potent antitumor effects in vitro and in vivo, recombinant IFNs have been used extensively over the years, alone or in

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